- It is used in the crafting of the Alkahest, Witherless Rose, Ethereal Talisman and Ethereal Amulet. It can also be used for crafting a beacon, which is from vanilla minecraft.
- Adding a Nether Star to a Tinkers' Construct tool as a modifier in a Tool Station or Tool Forge will give the tool one extra modifier slot.
- After acquiring two Nether Stars, Diamonds and Glowing Water can be generated for 9 experience levels by using an Uncrafting Table. This can be repeated indefinitely as long as the player has the levels and Soul Sand necessary to uncraft and resummon the Wither. Although this does make diamonds renewable as Soul Sand can be copied in a recipe involving Redstone, it would be more advisable to gain diamond gear by conquering Battle Towers and repairing old diamond tools with the Enchantment Table's repair feature due to the lower difficulty and unlikely chances of causing damage to terrain.